In this report, Jiang et al performed simultaneous recordings from inhibitory FS neurons and excitatory pyramidal neurons (PC) in human epileptic or non-epileptic cortical slices. They demonstrate for ...
Ca²⁺ influx into presynaptic nerve terminals activates synaptic vesicle exocytosis by triggering fast synchronous fusion and a slower asynchronous release pathway. In addition, a brief rise in Ca²⁺ ...
Synaptic communication is triggered by action potentials, but neurons also talk to each other in between action potentials. Specific intracellular-calcium sensors regulate these conversations.