In this interview, industry experts Mathieu Bennet and Dustin Whitson explore how automation and single-cell technologies are transforming high-throughput B-cell cloning for antibody discovery. Can ...

New study demonstrates how high-affinity B cells 'bank' their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design. A vaccine's ...

GPCRs represent one of the most important yet technically challenging classes of drug targets, largely due to difficulties in producing stable, native like antigens and generating high-quality ...

Capturing this mechanism in the lab may lead to more efficient vaccine strategies in the clinic. Our work shows how high-affinity B cells can bank really advantageous mutations by essentially cloning ...

Reproductive Cloning is the process of making a full living copy of an organism. Reproductive cloning of animals transplants nuclei from body cells into eggs that have had their nucleus removed. That ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...