A new editorial paper was published in Oncoscience, titled "PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs." While targeted cancer therapy is greatly ...

Researchers at University of Tsukuba have uncovered a master transcriptional regulator that controls rhizobial symbiosis between plants and nitrogen-fixing bacteria. By identifying an amino acid motif ...

In a recent study published in the journal Nucleic Acids Research, researchers investigate whether machine learning can identify pan-cancer mutational hotspots at persistent CCCTC-binding factor ...

Scheme 1: Inside activation of EGFR by PAR as indicated by Tyr-phosphorylation, potently inhibited by Pc(4-4). While targeted cancer therapy is greatly dependent on specific oncogenic pathways or ...