A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's. However, the protective blood-brain barrier (BBB) makes delivering fluorescent sensors ...

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in ...

Three-dimensional fluorescence imaging of neurons in Layer 5 of the cerebral cortex, captured by two-photon microscopy in mice expressing a fluorescent protein (Thy1-EYFP-H). SeeDB-Live clearing ...

Biomedical engineers at Duke University have developed a technique to noninvasively visualize the brain's waste-removal ...

Fluorescence images of the cerebral cortex of a Thy1-YFP-H transgenic mouse, before and after clearing with SeeDB-Live. SeeDB-Live enables real-time imaging of the living brain at greater depth and ...

A new randomized clinical trial from investigators at Mass General Brigham's Neuroscience Institute and Department of Psychiatry suggests that using personalized brain imaging to guide transcranial ...

A new randomized clinical trial from investigators at Mass General Brigham's Neuroscience Institute and Department of ...

It infects nearly one-third of the global population, yet its microscopic size makes the parasite difficult for scientists to study. That parasite is Toxoplasma gondii, a widespread organism that ...