Influence of Epithelial-Mesenchymal Transition on Risk of Relapse and Outcome to Eribulin or Cyclin-Dependent Kinase Inhibitors in Metastatic Breast Cancer Patients with NSCLC who had CSF collection ...

In advanced cancers, including breast, lung, and melanoma, leptomeningeal disease (LMD), a condition associated with rapid neurological deterioration, can develop. Treatment options remain limited, ...

CHICAGO -- Intracerebroventricular (ICV) delivery of bivalent CAR T-cells targeting EGFR and IL13Rα2 was feasible and appeared safe in patients with recurrent glioblastoma (GBM) in a phase I study ...

A blood stem cell donation can save the lives of people with leukemia. To collect these cells from the bloodstream, donors are given medication that mobilizes blood stem cells from the bone marrow. A ...

Spinraza was linked to changes in CSF biomarkers in SMA, some of which were associated with motor gains, but more research is ...

A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a subject of debate. Encased in the skull, perched atop the spine, the brain has a ...

Patients with NSCLC who had CSF collection as part of routine clinical care for suspected LMD were included in the study. CSF was evaluated for CTCs and cfDNA using a commercial assay (CNSide; Biocept ...