Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease. But many engineered immune cells lose strength quickly after they enter the body, especially ...

A tumor “don’t‑eat‑me” shield also hides pro‑immune danger signals; new antibodies that unmask this hidden cue could make cancers more vulnerable to immune attack.

Finding an effective treatment for osteosarcoma, the most common type of bone cancer in children and young adults, has puzzled medical researchers for 40 years. Now, a new study by researchers at Case ...

We are curing more cancers than we used to,” Cottrill said. “Recurrent cancers are more challenging to cure than cancers that ...

KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can exploit healthy lung cells to support metastatic tumor growth in the lungs.

A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells ...

A redesigned cancer immunotherapy is showing striking early results after decades of disappointment with similar drugs. Researchers engineered a more powerful CD40 agonist antibody and changed how ...

Scientists have discovered that cells can sense far beyond the surfaces they touch. While individual cancer cells can probe about 10 microns ahead by tugging on surrounding collagen fibers, clusters ...

CAR T therapy has been transformative in the battle against deadly cancers. Scientists extract a patient’s own immune cells, genetically engineer them to target a specific type of cancer, and infuse ...

Cancer cell-derived small extracellular vesicles (sEVs) can travel from distant tumors through the bloodstream and kidneys ...

A newly discovered genetic switch may allow scientists to dramatically amplify the cancer-killing power of natural immune cells by harnessing the body’s own signaling molecules. Credit: Shutterstock ...

T cells (red) attack cancer cell (white) / Rita Elena Serda, Duncan Comprehensive Cancer Center at Baylor College of Medicine, National Cancer Institute, NIH Share Lights, vitamin, action. A ...