Studying the spatial landscape of the genome can bring new insights into our understanding of the disease developments. Multiple methods of capturing the spatial landscape were introduced from 2002, ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by ...

Understanding how regulatory T cells (Tregs) develop and work is key to determining how they might be manipulated to encourage the destruction of cancer cells or prevent autoimmunity. Cell behavior is ...

Chinese researchers have developed a groundbreaking technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.

Scientists at the Salk Institute say they have discovered that the Foxp3 protein is essential for creating the unique chromatin architecture of regulatory T cells and, in turn, promoting their immune ...

A team of Chinese scientists has uncovered a hidden 3D structure in rice DNA that allows the crop to grow more grain while using less nitrogen fertilizer. The finding, published in Nature Genetics by ...

Researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each ...