Inside our cells, ribosomes—the tireless "protein factories" of life—have just shown off a new skill they haven't used in billions of years. A research team has become the first in the world to ...

Drug discovery demands speed and precision, with success often hinging on how quickly teams can move compounds through synthesis, purification, and testing. In this project, flexibility and agility ...

Cyclic peptides offer enhanced stability and bioavailability, but precise cyclization strategies and specialized synthetic techniques are required to maintain their biological activity. A recent ...

Scientists at Tokyo Institute of Technology have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using ...

Small-molecule drugs have been instrumental in alleviating a gamut of ailments, from heart disease to the humble headache, but some experts now think we’ve exhausted the number of targets those drugs ...

BioDuro, a research and CDMO group, opened a new peptide synthesis manufacturing facility at its campus in the Zhangjiang tech center in Shanghai. The facility expands the company’s peptide synthesis ...

Therapeutic peptides constitute an unusual drug category. Although most therapeutic peptides are synthetic, their molecular weights are well above those of small-molecule drugs, but well below those ...

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed a sustainable, biodegradable, biorecyclable material: high-entropy non-covalent cyclic ...

Scientists have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol ...