DNA-encoded chemical libraries (DELs) have emerged as a transformative technology in drug discovery, offering unparalleled efficiency in the identification of bioactive small molecules. By covalently ...

DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously.

CHENGDU, China--(BUSINESS WIRE)--HitGen and Fierce Biotech jointly release the Whitepaper: Advancing Drug Discovery through DNA-Encoded Library (DEL) Technology today. This whitepaper will provide the ...

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies. Such treatments, however, are very complex and ...

Participants received one to four doses of the treatment through intramuscular injection of DNA encoding two SARS-CoV-2 neutralizing mAbs, AZD5396 and AZD8076. This was followed by a brief electrical ...

Could the library of the future replace bookshelves with petri dishes? New research into the possibility of storing information in DNA has already preserved words by Shakespeare and Martin Luther King ...

In early-stage drug discovery, library size matters because biology is sparse. For most targets, only a tiny fraction of chemical space will bind at all, and an even smaller fraction will bind with ...

Researchers from the Henry and Marilyn Taub Faculty of Computer Science have developed an AI-based method that accelerates DNA-based data retrieval by three orders of magnitude while significantly ...

Researchers at the University of Geneva have built a molecular system that can tell the difference between a cancer cell and ...

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ingenious solution. A scientist examines a DNA (deoxyribonucleic acid) profile on ...