Demyelination in the central nervous system (CNS) underlies many human diseases, including multiple sclerosis (MS). We report here the findings of our study of the CNS demyelination process using ...

CNS remyelination is the regenerative process by which myelin sheaths are restored to demyelinated axons. Unlike the poor regeneration that occurs following neuronal injury, remyelination can occur as ...

The term demyelination refers to the loss of the myelin sheath that surrounds and protects axons in the central nervous system. Demyelination occurs as the result of diseases that damage the myelin ...

THE demyelinating diseases of the nervous system remain a challenge to scientific investigation and a stumbling block in medical therapy. Comprising an important group of neurologic disorders, they ...

In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader ...

Investigators at the National Institute of Biological Sciences in Beijing and China Agricultural University have identified mixed lineage kinase domain-like protein (MLKL) as an important player in ...