Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Gestational growth and development of bone is an understudied process compared to soft tissues and has implications for lifelong health. This study investigated growth and development of human fetal ...

New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation. A pair of proteins, YAP and TAZ, has been identified as ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

Tissue or organ targeted drug delivery holds the promise to increase the drug efficacy and reduce side effects. Unlike soft tissues, bone tissue possesses some specificity in cellular components, ...

The oldest collection of mass-produced prehistoric bone tools reveal that human ancestors were likely capable of more advanced abstract reasoning one million years earlier than thought, finds a new ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

If you have ever broken a bone, you quickly learn two things: it hurts a lot, and bones are living tissue that takes time to heal, but they do heal. A fractured femur, for instance, may take six ...

New publication outlines the stakeholder-driven, evidence-based process behind a global, multilingual platform for people living with osteoporosis and their caregivers. A new paper published in ...