Brain development from childhood through adolescence is crucial for understanding autism spectrum disorder (ASD). Yet how functional networks regulate developmental changes in brain morphology remains ...

Hundreds of genes have been linked to autism, yet the precise molecular and cellular mechanisms behind it remain largely ...

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and Ludwig Maximilian ...

Organoids have helped create a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development. This work provides new insights ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...

Many psychiatric disorders begin during adolescence, coinciding with the rapid development of brain white matter (WM). However, it remains unclear whether deviations from normal WM development during ...

A team of researchers from the University of Aberdeen has uncovered, for the first time, how genes linked to autism and intellectual disability may influence early brain development. Their work helps ...

An international research team identified hundreds of genes essential for the development of brain cells, including one gene linked to a severe neurodevelopmental disorder not previously described.

Researchers at the Central Institute of Mental Health (CIMH) in Mannheim, together with international partners, have developed patient-derived brain organoids for the first time in order to better ...

When brain development gets off to a bad start, the consequences are lifelong. One example is a condition called SCN2A haploinsufficiency, in which children are born with just one functioning copy of ...

An 8-month-old infant with severe genetic epilepsy has become the first patient in the world to receive an experimental gene ...