Hypertension affects 1 billion people world-wide, contributing to 5 million deaths annually from myocardial infarction, stroke, kidney failure and heart failure. Its causes have been obscure owing to ...

Congenital urinary tract obstruction is the single most important cause of childhood chronic kidney disease. We have previously demonstrated that human and primate fetal obstruction impairs the ...

The human kidney is made up of about a million nephrons, the filtering units of this complex and highly vascular organ. Each nephron is composed of a highly coiled tubule, one end of which forms a cup ...