Effective cancer immunotherapy relies not only on antigen recognition by T and B lymphocytes but also on co-stimulatory signals that reinforce activation, expansion and memory formation. T cells ...
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
A new cell therapy was able to tamp down the immune system’s overreaction to gluten in mouse models. (iStock / Getty Images Plus) For the 80 million people worldwide with celiac disease, the only ...
Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T stem cells undergo normal cell division. The findings, ...
A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...