An approach that identifies, and predicts compatibility between, chemical and enzyme-sequence spaces can streamline and reduce risk in the discovery of enzymes that can catalyse a desired reaction.
An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...
Figure 1: Enzyme complex showing nocardicin G (dark blue) positioned next to the 3-ACP group (green) in the enzyme active site. Reprinted with permission from Ref 1 ...
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