This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...