Use of a clinician-facing dashboard combined with a best practice alert helped increase rates of HLA-B*58:01 genetic testing among patients prescribed allopurinol.

The HLA-B27 genetic marker is known to be associated with increased risk for various arthropathies, including JIA. Whether the genetic marker's presence has prognostic value has been uncertain. In ...

There is no specific “diagnostic” or pathognomonic laboratory marker for ankylosing spondylitis/axial spondyloarthritis (AS/axSpA), and diagnosis is based on clinical history, physical examination and ...

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...

In patients with spondyloarthritis, onset of common musculoskeletal symptoms such as back pain led to diagnostic delays averaging over 7 years. Onset with extra-musculoskeletal manifestations such as ...