St. Jude Children's Research Hospital scientists have uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), ...

Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in ...

The Hedgehog (Hh) signalling pathway is a highly conserved mechanism that directs cell fate, patterning and tissue homeostasis throughout embryogenesis and adult life. Signalling is initiated when a ...

A study showed that arachidonic acid binds Smoothened to strengthen SHH signaling during heart and lung development.

St. Jude Children's Research Hospital scientists uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a ...

A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...

Mayo Clinic's Phospholipid Signaling in Embryonic Development and Human Diseases Lab led by Kun Ling, Ph.D., dissects the phosphoinositide-dependent ciliary trafficking machinery.