This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Researchers developed LS-170, an inhibitor of the ATAC complex, which suppressed oncogene expression and reduced tumor growth ...

In a groundbreaking advancement for cancer treatment, a research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has made significant strides ...

Researchers at Colorado State University have determined how to use artificial intelligence to modify antibodies so they act ...

Working model of the BrHDA6-BrSOT12 module in downy mildew resistance of B. rapa.

Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when ...

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...