This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...
Pharmacogenomic Strategies Provide a Rational Approach to the Treatment of Cisplatin-Resistant Patients With Advanced Cancer We used immunohistochemistry to assess histone 3 lysine 4 dimethylation ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...
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Chromosomes and spindles in mature oocytes are stabilized by histone modification, study shows
The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...
Chimeric antigen receptor (CAR)-T cell immunotherapy has considerably changed the landscape of treatment options for blood cancers. CAR-T therapy aims to redirect a patient’s T cells to recognize and ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...
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