Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

iXCells’ mission is to empower life science researchers and patient foundations to advance personalized therapies and accelerate discovery of better medicines for a healthier future. iXCells’ cell ...

One of the holy grails of biology is digitally simulating a living cell. If researchers can use computers to more accurately understand how new medicines would react in the body, that could give them ...

Yusuf Roohani, PhD, machine learning group lead at the Arc Institute, is among a team of researchers training artificial intelligence (AI) models with transcriptome data to predict how cell gene ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Early detection of safety liabilities of new therapies is a critical biopharmaceutical challenge. Addressing this challenge could significantly advance drug discovery. Advanced human cell models, ...

The authors emphasize regular genomic integrity assessments to ensure models remain representative of patient genetics. Additionally, selecting appropriate cell types proves crucial yet complex, ...

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair ...