In a novel study, researchers introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome. Unlike current methods that ...

Gain-of-function experiments can help researchers get ahead of viruses naturally gaining the ability to infect people in the wild. But they're also used for many other areas of study within biology.

Biosafety hawks were initially optimistic that the incoming second Trump administration would at last place binding constraints on so-called "dangerous gain-of-function" research, in which pathogens ...

The Trump administration is reportedly preparing an executive order curtailing funding of "gain-of-function" research on pandemic pathogens, in what would seem to be an effort to prevent the next ...

Stanley is an associate professor and Richard and Rhoda Goldman distinguished chair in the biological sciences as well as faculty director for the Alliance for Global Health and Science at the ...

LoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps explain how genetic changes ...