In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence ...

Microglia are the brain's immune cells that clean out debris, such as damaged proteins and old cell parts, to keep the organ ...

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...

Imagine your brain as a high-end restaurant. Normally, the kitchen is remarkably efficient: fresh ingredients (proteins) ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological ...

A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human ...

Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...

Clusterin, we’re sorry—we misjudged you. Long cast as Aβ’s villainous sidekick (Jan 2014 news; Apr 2023 news), the chaperone now looks more like a friendly superhero. Provided, that is, our genes let ...

Recently approved Alzheimer’s drugs offer a step forward for treating the disease, but new therapeutic strategies are needed to complement them and provide personalized therapeutic approaches. Mass ...