Here we describe lentivirus-infected cell microarrays for the high-throughput screening of gene function in mammalian cells. To create these arrays, we cultured mammalian cells on glass slides ...

Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...

Microarrays are a two-dimensional arrangement of biological samples, with samples placed in spots numbering in the thousands and organized into columns and rows. They allow for efficient analysis of ...

Microarrays can be manufactured to different sizes with the number of probes on a microarray ranging from ten to five million. The fabrication of microarrays, particularly how the probes are ...

Spectrum Solutions’ offerings enhanced by including CLIA/CAP laboratory testing, custom assay development, and manufacturing of industry-leading microarray chip technology. These valuable assets, ...

Although the superiority of expression-based biomarkers, as compared with traditional clinical staging, has been disputed, 33 a nationwide clinical trial is under way in the Netherlands in which ...

Different applications have different requirements, so researchers need to carefully weigh their options when deciding whether to switch to a new platform. [© WavebreakmediaMicro – Fotolia.com] With ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

For most researchers DNA microarrays are synonymous with high-throughput gene expression analysis. But they also are invaluable genotyping tools. Now that the International HapMap Project (see article ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the ...

AMSBIO reports that its extensive range of FDA tissue microarrays reliably enhances tissue cross-reactivity (TCR) and other target validation studies. These high-quality tissue microarrays (TMAs) ...