Droplet-based single-cell sequencing techniques rely on the fundamental assumption that each droplet encapsulates a single cell, enabling individual cell omics profiling. However, the inevitable issue ...
Single-cell multiomics provides a comprehensive view of the cellular heterogeneity and the complex interplay between multiple layers of cellular omics, namely genome, epigenome, transcriptome, and ...
Cells in multicellular organisms are diverse and highly specialized. Such a level of specialization is in part encoded in their spatial organization 1,2. Single-cell RNA-seq (scRNA-seq) methods have ...
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