Why do some people develop cancer while others, exposed to seemingly similar environments and living comparable lifestyles, ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

Mutation rates govern the introduction of genetic variation and influence evolutionary trajectories, disease susceptibility and species diversity. Rates are shaped by a balance between DNA damage, ...

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...

Scientists have identified an inherited genetic mutation that greatly increases the risk of lung cancer, even in people who have never smoked. The mutation involves the EGFR gene, which helps control ...

This mutation rate dictates how quickly species can adapt to changing environments. Supported by a combined $2.08 million in total NSF funding across partner institutions, the multi-institutional ...

This retrospective, observational study included patients 18 years or older at ER+/HER2– metastatic breast cancer diagnosis who initiated first-line therapy with aromatase inhibitors (AI) or selective ...

Every time a cell divides, its chromosomes must be distributed correctly between the two daughter cells. Central to this ...

A new study by scientists at City of Hope ® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals. Some study ...