A polygenic risk score was able to detect a high proportion of clinically significant prostate cancer. Cancer would not have been detected in 71.8% of patients with the use of PSA or MRI screening.

Allelica, a precision medicine company focused on genomic risk assessment for common diseases, today announced that it has entered into a commercial license agreement with Cambridge Enterprise, the ...

Please provide your email address to receive an email when new articles are posted on . Researchers said common risk variants help explain why epilepsy occurs in some family members and not others.

Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...

Please provide your email address to receive an email when new articles are posted on . A polygenic risk score that includes rare variants did not substantially improve osteoporosis or fracture risk ...

Individuals with a higher risk of primary open-angle glaucoma (POAG) could be identified using a polygenic risk score, recent study found. In complex diseases such as POAG, PRSs can be used to measure ...

Using polygenic risk scores along with positive family histories and breast cancer-associated gene mutations improves risk stratification for breast cancer screening. Compared with a lower polygenic ...