Bethesda, MD - Scientists have discovered a DNA sequence that is involved in controlling the timing of DNA replication. Because alterations in DNA replication timing are associated with cancer, this ...

Huge sections of the human genome are made up of highly repetitive sequences, areas where bases like ATATAT repeat in very long strings. For many years, scientists wrote these repetitive sequences off ...

The initiation of chromosome replication is exquisitely regulated in both time and location. It has been estimated that there are 200-400 autosomal replication sequence elements (ARSs) in the yeast ...

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the ...

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...

Inactivation of mismatch repair (MMR) causes inherited and sporadic cancers 1. These tumours exhibit microsatellite instability (MSI) - length alterations within short repeats. MSI is a diagnostic and ...