Sickle cell disease (SCD) is a group of hereditary red blood cell disorders. Sickle cell anemia is a type of SCD that occurs when a person inherits genes containing an atypical form of hemoglobin.

Sickle cell thalassemia occurs when you inherit both a sickle cell gene mutation and a thalassemia gene mutation. Symptoms are similar to other types of sickle cell disease but can vary depending on ...

It has been a medical mystery for 67 years, ever since the British geneticist Anthony Allison established that carriers of one mutated copy of the gene that causes sickle-cell anaemia are protected ...

Sickle cell disease is a hereditary condition, which means a person inherits it from their biological parents. The condition occurs when a person inherits two copies of the hemoglobin beta (HBB) gene ...

Thousands of years ago, a special child was born in the Sahara. At the time, this was not a desert; it was a green belt of savannas, woodlands, lakes and rivers. Bands of hunter-gatherers thrived ...

Sickle cell anemia (SCA) is an inherited disorder of red blood cells. Some parents may learn that their infant has this disorder after prenatal testing. Hospitals also test for SCA after birth as part ...

Exa-cel, a new CRISPR-based treatment, modifies the genes of the patient's stem cells to induce them to produce fetal hemoglobin. I have a long-standing interest in sickle cell anemia, a genetic ...

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

Sickle Cell Disease is an awful genetic disease that disproportionally affects black people. It's caused by a single-point mutation in DNA, which results in a modified hemoglobin protein, differing by ...

By Shreoshree Chakrabarty: Sickle Cell Disease (SCD) is a group of inherited blood disorders that affect the shape and function of red blood cells. The most severe form, Sickle Cell Anemia, occurs ...

UCSF Benioff Children’s Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...