The advantages and disadvantages of hot-melt extrusion in solid dispersion formulations. Solid dispersions represent a promising formulation approach for overcoming today's major challenge in ...

The use of solid dispersion technology to increase the bioavailability of poorly water-soluble drugs has always been limited by processing and scale-up difficulties. A new approach may help to ...

Raman imaging and scanning electron microscopy (SEM) was used to investigate acetaminophen solid dispersions prepared by hot melt extrusion (HME). This experiment confirmed that a high screw speed ...

Most of the time, only minimal volumes of the sample are available for particle size analysis. Typically, in catalysis and pharmaceutical industries, particle size analysis needs to be conducted at ...