Nature

Structure of the PIN/LC8 dimer with a bound peptide

The structure of the protein known both as neuronal nitric oxide synthase inhibitory protein, PIN (protein inhibitor of nNOS), and also as the 8 kDa dynein light chain (LC8) has been solved by X-ray ...
Nature

Structure of NFAT1 bound as a dimer to the HIV-1 LTR κB element

DNA binding by NFAT1 as a dimer has been implicated in the activation of host and viral genes. Here we report a crystal structure of NFAT1 bound cooperatively as a dimer to the highly conserved κB ...