Immunotherapy has transformed cancer care, offering a way to harness the body’s own immune system to fight tumors. But even with these advances, many patients still don’t respond. One major barrier to ...

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged ...

A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to ...

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

A landmark study due to start in the coming months aims to test a method for rejuvenating our immune system in older age. The ...

Researchers at Karolinska Institutet have uncovered how serotonin-related metabolism helps regulate an understudied immune ...

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while ...

cGAS-STING signaling exerts antitumor functions in cancer cells in an autonomous and non-autonomous manner. On the one hand, OIS secretes SASP in response to oncogenic stimuli to prevent cell ...