When a cell divides, a small section of the telomere of each chromosome is worn away. While most cells use the enzyme telomerase to mitigate this loss, about 10–15% of cancers use a different ...

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles.

Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to maintain long, healthy telomeres. When RPA malfunctions, telomeres can shorten ...

BUFFALO, NY — October 27, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the TRF1 telomere-binding protein leads to leaner mice ...

A model of the human telomerase complex highlights where RPA is predicted to dock. Three structural variants of telomerase that have been linked to patients with various diseases fall within this ...

A study by Children's Medical Research Institute (CMRI) researchers reveals a new group of proteins that guide the powerful enzyme telomerase, opening potential doors to novel treatments for cancer, ...

New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in our chromosomes may be responsible for serious - and sometimes deadly ...

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that guard our DNA and keep cells alive are constantly tweaking their structures ...

Transposons, or "jumping genes" – DNA segments that can move from one part of the genome to another – are key to bacterial evolution and the development of antibiotic resistance. Cornell University ...