Integral membrane proteins are inserted into the bacterial cytoplasmic membrane in a co-translational manner. Ribosomes that are synthesizing membrane proteins are targeted to the membrane by the ...

Protein biogenesis at the endoplasmic reticulum requires translocons comprising the Sec61 protein-conducting channel and several dynamically associated accessory factors. Here we used ...

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then ...

Chemists have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The feat required ...

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then ...

Credit: Reprinted by permission of Macmillian Publishers, LTD." /> Credit: Reprinted by permission of Macmillian Publishers, LTD. The paper: T. Hessa et al., ?Recognition of transmembrane helices by ...

Ludwig Maximilian University researchers have visualized the complex interplay between protein synthesis, transport and modification. All biological membranes are made up of a phospholipid bilayer, ...

(Nanowerk News) Proteins are the molecular building blocks and machines of the cell and are involved in virtually every process of life. After protein production, many proteins are equipped with ...

PASADENA, Calif.—Chemists at the California Institute of Technology (Caltech) have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows ...

(Nanowerk News) Chemists at the California Institute of Technology (Caltech) have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows ...