Associations of serum lipids with cholelithiasis from Mendelian randomization. (A) Causal effects of genetically−lowered lipids on cholelithiasis. (B) Results of multivariable Mendelian randomization ...

The principal novel finding of this study is that lifelong low levels of HDL cholesterol due to genetic variation in HDL cholesterol–related genes are not associated with the increased risk of type 2 ...

Obesity related to metabolic syndrome was found to have a causal relationship with colorectal cancer (CRC), although this causal relationship did not exist in the opposite direction. A study published ...

In a recent study published in the JAMA Network Open, researchers performed a genetic association study using a Mendelian Randomization (MR) framework to assess associations between genetically ...