Aromatase is localized in the endoplasmic reticulum where it is regulated by tissue-specific promoters that are in turn controlled by hormones, cytokines, and other factors.

Aromatase is also called estrogen synthetase or estrogen synthase, highlighting its primary role in estrogen biosynthesis. It is involved in the final steps of creating estrogens, a class of steroid …

Nov 25, 2025 · Aromatase, also known as estrogen synthase, is an enzyme that plays a central role in regulating the balance of sex hormones. It is a cytochrome P450 enzyme encoded by …

Apr 29, 2025 · Learn more about aromatase inhibitors, including the three types, why they’re used in breast cancer treatment, their side effects, and their benefits.

In both sexes, aromatase is found in a number of extragonadal sites, including bone, breast, adipose tissue and brain. This tissue-specific expression of aromatase maintains tight local …

Mutations in the aromatase gene (CYP19A1) can result in a lack of aromatase activity and, as a consequence, impairment in estrogen biosynthesis. The functional consequences of this …

Aromatase is an enzyme that plays a crucial role in the biosynthesis of estrogens from androgens. It is responsible for the conversion of testosterone and androstenedione into estradiol and …

Aromatase is responsible for turning female androgen and male testosterone into estrogen. Its main function may be to keep a balance between active amounts of cortisol and active …

Aromatase is a cytochrome P450, hemoprotein-containing enzyme, located in the endoplasmic reticulum, which catalyzes the rate-limiting step in the conversion of androgens …

Aromatase catalyzes three separate steroid hydroxylations involved in the conversion of androstenedione to estrone. The first two give rise to 19-hydroxy and 19-aldehyde structures, …