
Adipose triglyceride lipase - Wikipedia
Adipose Triglyceride Lipase (ATGL) can undergo activation through two different pathways: transcriptionally and through post-translational modification.
Adipose Triglyceride Lipase Regulation: An Overview - PMC
Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis and produces FAs used for energy …
What Is ATGL and Its Role in Fat Metabolism? - Biology Insights
Jul 26, 2025 · Adipose Triglyceride Lipase (ATGL) is an enzyme that helps manage fat in our bodies, influencing energy levels and metabolic health. It breaks down stored fats to supply …
Adipose Triglyceride Lipase - an overview | ScienceDirect Topics
Adipose triglyceride lipase (ATGL) is defined as a key enzyme that initiates the hydrolysis of triglycerides to release fatty acids, playing a crucial role in energy metabolism and …
PNPLA2 gene: MedlinePlus Genetics
The PNPLA2 gene provides instructions for making an enzyme called adipose triglyceride lipase (ATGL). The ATGL enzyme plays a role in breaking down fats called triglycerides, which are …
S-acylation of ATGL is required for lipid droplet homoeostasis in ...
Aug 14, 2024 · Our results reveal S-acylation as a mode of regulation of ATGL function and LD homoeostasis. Modulating this pathway may offer therapeutic potential for treating diseases …
The Biochemistry of ATGL: A Deep Dive - numberanalytics.com
Jun 9, 2025 · ATGL is a triglyceride lipase that catalyzes the hydrolysis of triglycerides to diacylglycerols and free fatty acids. The enzyme exhibits a high degree of substrate specificity, …
Recent Advances on the Role of ATGL in Cancer - PMC
Adipose triglyceride lipase, also known as patatin-like phospholipase= domain-containing protein 2 and Adipose triglyceride lipase (ATGL), as an essential lipid metabolism-regulating enzyme …
Adipose Triglyceride Lipase: Function and Health Impact
Jul 22, 2025 · Adipose triglyceride lipase (ATGL) is the primary enzyme that initiates the breakdown of fat stored within the body’s adipose tissue (fat cells). It controls the release of …
Adipose Triglyceride Lipase in Hepatic Physiology and ... - MDPI
Dec 31, 2021 · Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme that catalyzes the first step of TG breakdown to glycerol and fatty acids.