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  1. Decay-accelerating factor - Wikipedia

    Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. [5] DAF regulates the complement system on the cell surface. It …

  2. CD55 in cancer: Complementing functions in a non-canonical manner

    Apr 24, 2024 · CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via …

  3. CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis

    Jul 6, 2017 · We identified homozygous loss-of-function mutations in the gene encoding CD55 (decay-accelerating factor), which lead to loss of protein expression. Patients’ T lymphocytes showed …

  4. CD55 Gene - GeneCards | DAF Protein | DAF Antibody

    Jan 14, 2026 · Complete information for CD55 gene (Protein Coding), CD55 Molecule (Cromer Blood Group), including: function, proteins, disorders, pathways, orthologs, and expression.

  5. CD55 protein expression summary - The Human Protein Atlas

    High membranous expression in most epithelial cells, trophoblasts and alveolar cells with distinct positivity in connective tissue. Main subcellular location based on data generated in the subcellular …

  6. CD55 may be a new target for colorectal cancer treatment

    Jul 2, 2025 · CD55 significantly promotes CT26 proliferation and migration ability. CD55 is a potential tumor promoter and diagnostic marker for colorectal cancer.

  7. Mapping CD55 Function - Journal of Biological Chemistry

    Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many …

  8. CD55 in cancer: Complementing functions in a non-canonical manner

    Dec 28, 2022 · CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via …

  9. CD55 in cancer: Complementing functions in a non-canonical manner

    Dec 28, 2022 · Here, we review the unexpected roles of CD55 in cancer including the roles of canonical and noncanonical pathways that CD55 orchestrates. We will highlight opportunities for therapeutic …

  10. Frontiers | The genetic and epigenetic regulation of CD55 and its ...

    Jan 18, 2023 · CD55 plays an important role in the development of colon cancer. This study aims to evaluate the expression of CD55 in colon cancer and discover how it is regulated by transcriptional …