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Vaginal estradiol cream is one of the most underused tools in perimenopause. As estrogen levels fluctuate and decline, vaginal and urinary tissues lose thickness, elasticity, and moisture. This can lead to dryness, irritation, painful intercourse, and recurrent urinary symptoms. Low-dose vaginal estradiol works locally to support tissue health, improve comfort, and protect the vaginal and urinary environment, often with minimal systemic absorption. For many women, the impact is subtle but powerf
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